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5-Fluoroisatonic anhydride

Product Name
5-Fluoroisatonic anhydride
CAS No.
321-69-7
Chemical Name
5-Fluoroisatonic anhydride
Synonyms
6-fluoro-2H-benzo[d][1,3]oxazine-2,4(1H)-dione;5-FLUOROISATOIC ANHYDRIDE;NSC 149815;Flumazenil Impurity 15;6-FLUORO ISATIN ANHYDRIDE;5-FLUOROISATONIC ANHYDRIDE;6-fluoro-1H-3,1-benzoxazine-2,4-dione;6-Fluorobenzo[d][1,3]oxazine-2,4-dione;6-fluoro-1H-3,1-benzoxazine-2,4-quinone;6-FLUORO-2H-3,1-BENZOXAZINE-2,4(1H)-DIONE
CBNumber
CB5379596
Molecular Formula
C8H4FNO3
Formula Weight
181.12
MOL File
321-69-7.mol
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5-Fluoroisatonic anhydride Property

Melting point:
259-262°C
Density 
1.502±0.06 g/cm3(Predicted)
storage temp. 
Inert atmosphere,Room Temperature
solubility 
soluble in DMSO
form 
powder
pka
9.61±0.20(Predicted)
color 
Off-white to pale yellow
CAS DataBase Reference
321-69-7(CAS DataBase Reference)
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Safety

Risk Statements 
36/37/38
Safety Statements 
26-36
HazardClass 
IRRITANT
HS Code 
2934999090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

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N-Bromosuccinimide Price

TRC
Product number
F592025
Product name
5-FluoroisatoicAnhydride
Packaging
2g
Price
$210
Updated
2021/12/16
AK Scientific
Product number
Y7452
Product name
6-Fluoroisatoicanhydride
Packaging
25g
Price
$211
Updated
2021/12/16
ChemScene
Product number
CS-W005876
Product name
5-Fluoroisatoicanhydride
Purity
≥98.0%
Packaging
25g
Price
$318
Updated
2021/12/16
Matrix Scientific
Product number
057951
Product name
6-Fluoro-1H-benzo[d][1,3]oxazine-2,4-dione
Purity
99%
Packaging
100g
Price
$474
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
HCH0025236
Product name
6-FLUORO ISATIN ANHYDRIDE
Purity
95.00%
Packaging
1G
Price
$626.01
Updated
2021/12/16
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5-Fluoroisatonic anhydride Chemical Properties,Usage,Production

Chemical Properties

Dark yellow Solid

Uses

5-Fluoroisatoic Anhydride is a versatile pharmaceutical intermediate used in the preparation of insulin secretagogues, HCV polymerase inhibitors, anxiolytic agents and other bioactive compounds.

Preparation

5-Fluoroisatonic anhydride is prepared from 5-fluoro indole (9d) by stirring in a 4:1 mixture of DMF/H2O for 16 h at room temperature.
1 H NMR (DMSO-d6): δ11.19 (s, br., 1H), 7.36 (dd, J = 8.4, 2.6 Hz, 1H), 6.87 (dt, J = 8.4, 2.2 Hz, 1H), 6.74 (dd, J = 9.3, 2.2 Hz, 1H).

5-Fluoroisatonic anhydride Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from 5-Fluoroisatonic anhydride manufacturers

Career Henan Chemical Co
Product
5-Fluoroisatonic anhydride 321-69-7
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
G/KG/T
Release date
2019-12-24

321-69-7, 5-Fluoroisatonic anhydrideRelated Search:


  • 6-FLUORO-2H-3,1-BENZOXAZINE-2,4(1H)-DIONE
  • 6-fluoro-1H-benzo[d][1,3]oxazine-2,4-dione
  • 6-fluoro-1H-3,1-benzoxazine-2,4-dione
  • 6-fluoro-1H-3,1-benzoxazine-2,4-quinone
  • 6-FLUORO ISATIN ANHYDRIDE
  • 5-FLUOROISATOIC ANHYDRIDE
  • 5-FLUOROISATONIC ANHYDRIDE
  • 6-Fluorobenzo[d][1,3]oxazine-2,4-dione
  • NSC 149815
  • 6-fluoro-2,4-dihydro-1H-3,1-benzoxazine-2,4-dione
  • 6-Fluoro-2H-3,1-benzoxazine-2,4(1H)-dione, 6-Fluoro-1H-benzo[d][1,3]oxazine-2,4-dione
  • 2H-3,1-Benzoxazine-2,4(1H)-dione, 6-fluoro-
  • 6-fluoro-2H-benzo[d][1,3]oxazine-2,4(1H)-dione
  • Flumazenil Impurity 15
  • 321-69-7
  • Miscellaneous
  • Aromatics
  • Heterocycles
  • Intermediates & Fine Chemicals
  • Pharmaceuticals